Clinico histopathological spectrum of cutaneous vasculitis

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Clinico histopathological spectrum of cutaneous vasculitis

Cutaneous Vasculitis is the inflammation of vessel walls which leads to hemorrhagic or ischemic events.

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The histopathological classification of cutaneous vasculitis depends on the vessel size and the dominant immune The histopathological classification of cutaneous vasculitis depends on the vessel size and the dominant immune cell mediating the inflammation.

We studied the etiological factors and clinico-pathological spectrum of patients with cutaneous vasculitis at a tertiary referral centre of north India. Skin biopsies of all patients with clinically suspected cutaneous vasculitis presenting over 5 years, between were reviewed.

Cutaneous vasculitis was classified on the basis of etiology primary or secondaryon the basis of size of vessel wall as well as on the dominant inflammatory cell infiltrating the vessels. Clinically, vasculitis was primary Skin biopsy remains the gold standard for diagnosing cutaneous vasculitis.

Small vessel vasculitis was the most common type of cutaneous vasculitis with the dominant cell type being neutrophilic. Eosinophilic infiltrate was exclusively associated with primary vasculitis.

Cutaneous vasculitis, Small vessel vasculitis, Skin biopsy.Three patients with systemic complications of mononeuritis multiplex (two of three), interstitial pulmonary fibrosis (two of three) and abdominal microaneurysms (one of three) died within 1 year of onset of the cutaneous vasculitis.

Material & Methods

Cutaneous vasculitis has protean clinical manifestations. It may be idiopathic or associated with a spectrum of conditions such as infections, drugs, etc.

Skin is involved in both small vessel vasculitis (SVV) and medium vessel vasculitis (MVV). A total of 37 cases of cutaneous vasculitis were reported during the study period.

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Only 3 (%) of the patients were less than 20 years of age. The highest frequency of cutaneous vasculitis was among patients between the ages of 21 and 40 years (%), followed by the 41 to 60 years age group with 13 (%) patients.

Although the vessels involving vasculitis in patients with RA range from small skin vessels to the aortic root, 18, 22 vessels in the skin were the most frequently affected 1, 3, and were usually initially involved in patients with RV. 3, 8, 9 In our study, among nine patients with other extra‐articular complications, skin involvement was the initial manifestation in six patients.

Clinico histopathological spectrum of cutaneous vasculitis

In contrast, pulmonary . clinico-histopathological spectrum of cutaneous vasculitis: a retrospective study of 62 cases more by editor International Journal of Clinical & Biomedical Resaerch (IJCBR) and Sohaib Ahmad ABSTRAC¬T Context: Cutaneous Vasculitis is the inflammation of vessel walls which leads to .

Context: Cutaneous Vasculitis is the inflammation of vessel walls which leads to hemorrhagic or ischemic events. The histopathological classification of cutaneous vasculitis depends on the vessel size and the dominant immune cell mediating the inflammation.

Object: We studied the etiological factors.

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