Use an editor to spell check essay. Massive advertising campaigns mounted by major pharmaceutical corporations would have you believe that the only way to battle and control your depression is to take one of their drug concoctions. Their drugs are designed to correct an imbalance in serotonin, a naturally occurring chemical in the body.
Share via Email This article is over 6 months old It is likely that in the UK alone 1 million more people a year should have access to either drugs or psychotherapy for depression, say experts.
Millions more people around the world should be prescribed pills or offered talking therapies, which work equally well for moderate to severe depression, say the doctors, noting that just one in six people receive proper treatment in the rich world — and one in 27 in the developing world.
If cancer or heart patients suffered this level of under-treatment, there would be a public outcry, they say. The choice will need to be made by doctor and patient.
Some doctors and patients have doubts over whether they work at all and point to the big placebo effect — in trials, those given dummy pills also improve to some degree. Some people suspect drug companies of fiddling trial results. Some patients simply do not want to take pills for a mental health condition.
The study published in the Lancet took six years, Cipriani said, and included all the published and unpublished data that the scientists could find. It was carried out by a team of international experts.
They looked at results after eight weeks of more than trials involving either a drug versus placebo or comparing two different medicines. The most famous antidepressant of them all, Prozac — now out of patent and known by its generic name, fluoxetine — was one of the least effective but best tolerated, measured by a low drop-out rate in the trials or fewer side-effects reported.
The most effective of the drugs was amitriptyline, which was the sixth best tolerated. Antidepressant league table In a commentary in the journal, Sagar Parikh from the University of Michigan in the USA and Sidney Kennedy from the University of Toronto in Canada pointed out that three drugs scored best for efficacy and tolerability: Three others scored particularly poorly: But Cipriani said any of the drugs might still have their uses.
The trial data cannot show which drug would be likely to work best for any one individual. Antidepressants and psychological therapies — of which the most frequently used is CBT cognitive behaviour therapy — have similar success rates.
New treatments are badly needed, the experts say. Most of the drugs in the study are known as SSRIs, which are thought to work by increasing levels of a chemical messenger called serotonin in the brain, but nobody knows for certain.
However, the doubts and controversy over antidepressants, allied to the difficulties in discovering new neurological drugs, have led to the drug companies quitting a field that once — after the launch of Prozac — looked likely to be very lucrative for them.
How do antidepressants actually work? Dean Burnett Read more Other experts said the study was of major importance. Importantly, the paper analyses unpublished data held by pharmaceutical companies, and shows that the funding of studies by these companies does not influence the result, thus confirming that the clinical usefulness of these drugs is not affected by pharma-sponsored spin.
Depression causes misery to countless thousands every year and this study adds to the existing evidence that effective treatments are available. The research should reassure patients and doctors, she said.
It should never be swept under the carpet or ignored. In Australia, the crisis support service Lifeline is on 13 11 Other international suicide helplines can be found at www.May 16, · Meta-analyses of antidepressant medications have reported only modest benefits over placebo treatment, and when unpublished trial data are included, the benefit falls below accepted criteria for clinical significance.
Yet, the efficacy of the antidepressants may also depend on the severity of initial depression scores. Nov 07, · The authors of an essay are challenging the assertion that depression results from an imbalance in the brain chemical serotonin and related chemicals.
Mar 11, · Antidepressants Research Paper. consisting of patients treated with active antidepressant drugs, to determine the effects, compared to those of other patients treated with a placebo such as a sugar pill.
Research Paper on Antidepressants Essay on Saving Private Ryan Research Paper on Anesthesiology. Effectiveness of Antidepressant Drugs Essay example Words | 2 Pages.
Effectiveness of Antidepressant Drugs In Issue 13 of Taking Sides, the controversial question Have Antidepressant Drugs Proven to be Effective is analyzed.
About one in 10 Americans takes an antidepressant, now the most commonly prescribed type of drug in the U.S., according to research published in in the Archives of General Psychiatry.
Much of. One of the problems with antidepressant drugs is that most of them hinder zinc absorption in the body. Good sources of zinc include, shellfish, mushrooms, soy beans, sesame seeds, cocoa, sunflower seeds, rice and whole wheat bread to name a few.